Genome Guardian 2 cover

Genome Guardian 2

11 Oct 2026 · (31 days ago) · Full Release

Alpherior

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0 IVGDB Score

COMBINE WEAPONS in the microscopic shooter with macroscopic depth. BUILD YOUR NANOBOT from hundreds of parts. SURVIVE the microbial onslaught once more in this psychedelic dive to the Abyss, full of mutations, minerals, anomalies and powerup polyps. SHMUP mode turns it into a vertical shoot 'em up!

Need a rig? Gaming PCs, handhelds & where to buy →

Developer & Publisher: Alpherior

About

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About this game

Dive back into the microscopic world, radiating with bioluminescent life and unspeakable horrors.Research permanent upgrades to survive a variety of microbes & modes in this massively expanded follow-up to Genome Guardian.

Build your own biomechanical death machine from different parts to define how it shoots, behaves & moves!Make stationary turrets, psychic water sprinkler motorbikes, or maybe a dual-wielding fidget spinner Gundam.

Easily recreate your favourite turrets from the first game…or combine em' all into one frankenstein monstrosity

Save/Load 24 loadouts

Paint & Pattern customization

Pair DNA nucleotides A (rapidfire), C (precision), G (spread), T (explosive) to discover 70 hybrid bioweapons!

Shotgun + Bomb mix explosives with spread for Blast Shotgun!

SMG + Pistol make an accurate, fast-firing Scout Rifle!

Blast Shotgun + Scout Rifle = something a whole lot crazier!

20-minute runs you can save & resume at any time + improved Endless Mode

Complete side objectives during runs for extra cash

Mine mineral deposits for resources

Trigger powerful Gadget active abilities

Test discovered weapons in the Database

100 bassy electronic tunes with in-game Jukebox accessible any time + Streamer Mode

Auto aim/fire toggles

Localization in 10 languages

Full rebinding for keyboard & gamepad

400% better performance/framerate on high & low-end PCs

Accessibility for colourblindness, motion sickness & arachnophobia

100 Steam achievements

Cloud Save

Plays great on Steam Deck!

Trailers

▶ Watch trailer↗

System requirements

Minimum: Requires a 64-bit processor and operating system OS: Windows 10 Memory: 4096 MB RAM Storage: 1000 MB available space

Features & accessibility

PC system requirements

Minimum: Requires a 64-bit processor and operating system OS: Windows 10 Memory: 4096 MB RAM Storage: 1000 MB available space

Where to buy

official stores
SteamView store →

Reviews

Screenshots

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Aggregated from: steam